Sarah Guthrie
Professor of Developmental Neuroscience (Neuroscience)
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T: +44 (0)1273 872843

Selected publications

Article

Astick, Marc, Tubby, Kristina, Mubarak, Waleed M, Guthrie, Sarah and Price, Stephen R (2014) Central topography of cranial motor nuclei controlled by differential cadherin expression. Current Biology, 24 (21). pp. 2541-2547. ISSN 0960-9822

Tripathi, Vineeta Bhasker, Baskaran, Pranetha, Shaw, Christopher E and Guthrie, Sarah (2014) Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo. Neurobiology of Disease, 65. pp. 25-34. ISSN 0969-9961

Wanner, Sarah J, Saeger, Ivan, Guthrie, Sarah and Prince, Victoria E (2013) Facial motor neuron migration advances. Current Opinion in Neurobiology, 23 (6). pp. 943-950. ISSN 0959-4388

Clark, Christopher, Austen, Oliver, Poparic, Ivana and Guthrie, Sarah (2013) α2-chimaerin regulates a key axon guidance transition during development of the oculomotor projection. Journal of Neuroscience, 33 (42). pp. 16540-16551. ISSN 0270-6474

Miyake, Noriko, Chilton, John, Psatha, Maria, Cheng, Long, Andrews, Caroline, Chan, Wai-Man, Law, Krystal, Crosier, Moira, Lindsay, Susan, Cheung, Michelle, Guthrie, Sarah and et al, (2008) Human CHN1 mutations hyperactivate 2-chimaerin and cause Duane's retraction syndrome. Science, 321 (5890). pp. 839-843. ISSN 0036-8075

Guthrie, Sarah (2007) Patterning and axon guidance of cranial motor neurons. Nature Reviews Neuroscience, 8 (11). pp. 859-871. ISSN 1471-003X

Zhu, Yan, Guthrie, Sarah and Murakami, Fujio (2006) Ephrin A/EphA controls the rostral turning polarity of a lateral commissural tract in chick hindbrain. Development, 133 (19). pp. 3837-3846. ISSN 0950-1991

Coppola, Eva, Pattyn, Alexandre, Guthrie, Sarah C, Goridis, Christo and Studer, Michèle (2005) Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO Journal, 24 (24). pp. 4392-4403. ISSN 0261-4189

Hammond, Rachel, Vivancos, Valerie, Naeem, Arifa, Chilton, John, Mambetisaeva, Elvira, Andrews, William, Sundaresan, Vasi and Guthrie, Sarah (2005) Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain. Development, 132 (20). pp. 4483-4495. ISSN 0950-1991

Prin, Fabrice, Ng, Keat-Eng, Thaker, Uma, Drescher, Uwe and Guthrie, Sarah (2005) Ephrin-As play a rhombomere-specific role in trigeminal motor axon projections in the chick embryo. Developmental Biology, 279 (2). pp. 402-419. ISSN 00121606

Guthrie, Sarah (2004) Axon guidance: mice and men need rig and robo. Current Biology, 14 (15). R632-R634. ISSN 0960-9822

Chilton, John Kevin and Guthrie, Sarah (2004) Development of oculomotor axon projections in the chick embryo. The Journal of Comparative Neurology, 472 (3). pp. 308-317. ISSN 0021-9967

Guthrie, Sarah (2004) Neuronal development: putting motor neurons in their place. Current Biology, 14 (4). R166-R168. ISSN 0960-9822

Chilton, John K and Guthrie, Sarah (2003) Cranial expression of class 3 secreted semaphorins and their neuropilin receptors. Developmental Dynamics, 228 (4). pp. 726-733. ISSN 1058-8388

Knoll, Bernd, Schmidt, Hannes, Andrews, William, Guthrie, Sarah, Pini, Adrian, Sundaresan, Vasi and Drescher, Uwe (2003) On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. Development, 130 (21). pp. 5073-5082. ISSN 0950-1991

Guidato, Sonia, Prin, Fabrice and Guthrie, Sarah (2003) Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and hoxa3. Development, 130 (13). pp. 2981-2996. ISSN 0950-1991

Guidato, Sonia, Barrett, Camilla and Guthrie, Sarah (2003) Patterning of motor neurons by retinoic acid in the chick embryo hindbrain in vitro. Molecular and Cellular Neuroscience, 23 (1). pp. 81-95. ISSN 1044-7431

Zhu, Yan, Khan, Khurram and Guthrie, Sarah (2003) Signals from the cerebellum guide the pathfinding of inferior olivary axons. Developmental Biology, 257 (2). pp. 233-248. ISSN 0012-1606

Hernández-Montiel, Hebert L, Meléndez-Herrera, Esperanza, Cepeda-Nieto, Ana C, Mejía-Viggiano, Carmen, Larriva-Sahd, Jorge, Guthrie, Sarah and Varela-Echavarría, Alfredo (2003) Diffusible signals and fasciculated growth in reticulospinal axon pathfinding in the hindbrain. Developmental Biology, 255 (1). pp. 99-112. ISSN 0012-1606

Irving, Carol, Malhas, Amar, Guthrie, Sarah and Mason, Ivor (2002) Establishing the trochlear motor axon trajectory: role of the isthmic organiser and Fgf8. Development, 129 (23). pp. 5389-5398. ISSN 0950-1991

Zhu, Yan and Guthrie, Sarah (2002) Expression of the ETS transcription factorER81 in the developing chick and mouse hindbrain. Developmental Dynamics, 225 (3). pp. 365-368. ISSN 1058-8388

Guthrie, Sarah (2002) Neuronal development: sorting out motor neurons. Current Biology, 12 (14). R488-R490. ISSN 0960-9822

Naeem, Arifa, Abbas, Leila and Guthrie, Sarah (2002) Comparison of the effects of HGF, BDNF, CT-1, CNTF, and the branchial arches on the growth of embryonic cranial motor neurons. Journal of Neurobiology, 51 (2). pp. 101-114. ISSN 0022-3034

Barrett, Camilla and Guthrie, Sarah (2001) Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain. Mechanisms of Development, 106 (1-2). pp. 163-166. ISSN 0925-4773

Jacob, John, Hacker, Adam and Guthrie, Sarah (2001) Mechanisms and molecules in motor neuron specification and axon pathfinding. BioEssays, 23 (7). pp. 582-595. ISSN 0265-9247

Guthrie, Sarah (2001) Axon guidance: robos make the rules. Current Biology, 11 (8). R300-R303. ISSN 0960-9822

Küry, Patrick, Gale, Nick, Connor, Robert, Pasquale, Elena and Guthrie, Sarah (2000) Eph receptors and ephrin expression in cranial motor neurons and the branchial arches of the chick embryo. Molecular and Cellular Neuroscience, 15 (2). pp. 123-140. ISSN 1044-7431

Guthrie, Sarah (1999) Axon guidance: starting and stopping with slit. Current Biology, 9 (12). R432-R435. ISSN 0960-9822

Warrilow, Joanne and Guthrie, Sarah (1999) Rhombomere origin plays a role in the specificity of cranial motor axon projections in the chick. European Journal of Neuroscience, 11 (4). pp. 1403-1413. ISSN 0953-816X

Hacker, A and Guthrie, S (1998) A distinct development programme for the cranial paraxial mesoderm. Development (125). pp. 3461-3472. ISSN 0950-1991

Pringle, Nigel P, Guthrie, Sarah, Lumsden, Andrew and Richardson, William D (1998) Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes. Neuron, 20 (5). pp. 883-893. ISSN 0896-6273

Herbrandt, H, Guthrie, S, Hadrys, T, Hoffman, S, Arnold, H H, Rinkwitz-Brandt, S and Bober, E (1998) Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo. Development, 125. pp. 645-654. ISSN 0950-1991

Varela-Echavarria, A and Guthrie, S (1997) Molecules making waves in axon guidance. Genes & Development, 11 (5). pp. 545-557. ISSN 0890-9369

Varela-Echavarría, Alfredo, Tucker, Anna, Püschel, Andreas W and Guthrie, Sarah (1997) Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D. Neuron, 18 (2). pp. 193-207. ISSN 0896-6273

Guthrie, Sarah (1997) Axon guidance: netrin receptors are revealed. Current Biology, 7 (1). R6-R9. ISSN 0960-9822

Tucker, Anna, Lumsden, Andrew and Guthrie, Sarah (1996) Cranial motor axons respond differently to the floor plate and sensory ganglia in collagen gel co-cultures. European Journal of Neuroscience, 8 (5). pp. 906-916. ISSN 0953-816X

Pringle, Nigel P, Yu, Wei-Ping, Guthrie, Sarah, Lumsden, Andrew, Roelink, Henk, Peterson, Alan C and Richardson, William D (1996) Determination of neuroepithelial cell fate: induction of the oligodenrocyte lineage by ventral midline cells and sonic hedgehog. Developmental Biology, 177 (1). pp. 30-42. ISSN 0012-1606

Guthrie, Sarah (1996) Patterning the hindbrain. Current Opinion in Neurobiology, 6 (1). pp. 41-48. ISSN 0959-4388

Guthrie, Sarah and Pini, Adrian (1995) Chemorepulsion of developing motor axons by the floor plate. Neuron, 14 (6). pp. 1117-1130. ISSN 0896-6273

Mahood, R, Kiefer, P, Guthrie, S, Dickson, C and Mason, I (1995) Multiple roles for FGF-3 during cranial nerve development in the chicken. Development (121). pp. 1399-1410. ISSN 0950-1991

Guthrie, Sarah (1995) The status of the neural segment. Trends in Neurosciences, 18 (2). pp. 74-79. ISSN 0166-2236

Simon, Horst, Guthrie, Sarah and Lumsden, Andrew (1994) Regulation of SC1/DM-GRASP during the migration of motor neurons in the chick embryo brain stem. Journal of Neurobiology, 25 (9). pp. 1129-1143. ISSN 0022-3034

Guthrie, Sarah and Lumsden, Andrew (1994) Collagen gel coculture of neural tissue. Neuroprotocols, 4 (2). pp. 116-120. ISSN 1058-6741

Guthrie, S, Prince, V and Lumsden, A (1993) Selective dispersal of avian rhombomere cells in orthotopic and heterotopic grafts. Development (118). pp. 527-538. ISSN 0950-1991

Guthrie, Sarah (1992) Lineage in the cerebral cortex: when is a clone not a clone? Trends in Neurosciences, 15 (8). pp. 273-275. ISSN 0166-2236

Guthrie, Sarah, Muchamore, Ian, Kuroiwa, Atsushi, Marshall, Heather, Krumlauf, Robb and Lumsden, Andrew (1992) Neuroectodermal autonomy of Hox-2.9 expression revealed by rhombomere transpositions. Nature, 356 (6365). pp. 157-159. ISSN 0028-0836

Guthrie, S and Lumsden, A (1992) Motor neuron pathfinding following rhombomere reversals in the chick embryo hindbrain. Development (114). pp. 663-673. ISSN 0950-1991

Guthrie, Sarah, Butcher, Matthew and Lumsden, Andrew (1991) Patterns of cell division and interkinetic nuclear migration in the chick embryo hindbrain. Journal of Neurobiology, 22 (7). pp. 742-754. ISSN 0022-3034

Guthrie, Sarah and Lumsden, Andrew (1991) Formation of regeneration of rhombomere boundaries in the developing chick hindbrain. Development, 112 (1). pp. 221-229. ISSN 0950-1991

Guthrie, Sarah (1991) Horizontal and vertical pathways in neural induction. Trends in Neurosciences, 14 (4). pp. 123-126. ISSN 0166-2236

Lumsden, Andrew and Guthrie, Sarah (1991) Alternating patterns of cell surface properties and neural crest cell migration during segmentation of the chick hindbrain. Development (113). pp. 9-15. ISSN 0950-1991

Risek, Boris, Guthrie, Sarah, Kumar, Nalin and Gilula, Norton B (1990) Modulation of gap junction transcript and protein expression during pregnancy in the rat. Journal of Cell Biology, 110 (2). pp. 269-282. ISSN 0021-9525

Guthrie, Sarah (1989) Retinal axon guidance: near or far? Trends in Neurosciences, 12 (12). pp. 481-482. ISSN 0166-2236

Guthrie, S and Gilula, N (1989) Gap junctional communication and development. Trends in Neurosciences, 12 (1). pp. 12-16. ISSN 0166-2236

Guthrie, Sarah C (1985) Cell migration in the patterning of the nervous system of Hydra. Trends in Neurosciences, 8. pp. 306-309. ISSN 0166-2236

Guthrie, Sarah C (1985) Molecular markers in sea urchin development. Trends in Neurosciences, 8. pp. 185-187. ISSN 0166-2236

Guthrie, Sarah C (1984) Patterns of junctional communication in the early amphibian embryo. Nature, 311 (5982). pp. 149-151. ISSN 0028-0836

Guthrie, Sarah C (1984) Membrane excitability in cleavage-arrested, differentiated cells. Trends in Neurosciences, 7 (6). pp. 182-183. ISSN 0166-2236

Book Section

Montague, Karli, Guthrie, Sarah and Poparic, Ivana (2017) In vivo and in vitro knockdown approaches in the avian embryo as a means to study semaphorin signaling. In: Semaphorin signaling. Methods in molecular biology, 1493 . Humana Press, New York, US, pp. 403-416. ISBN 9781493964468