photo of Frances Pearl

Dr Frances Pearl

Post:Bioinformatics Academic Research Manager (Biochemistry)
Other posts:Associate Tutor (Life Sciences)
 Facility Manager (Biochemistry)
Location:Chichester 2 2r316
Email:F.Pearl@sussex.ac.uk

Telephone numbers
Internal:6631
UK:01273 876631
International:+44 1273 876631
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Biography

Educational Background

  • BSc Chemistry, 1st Class. UMIST
  • PhD, University College London  (Dame Janet Thornton FRS) Analysis of alpha helices and their interactions.

 

Employment Background

After my PhD I spent 7 years as the CATH database manager at UCL. The CATH database classifies protein structural domains into structural and evolutionary families. I ran the CATH update team and developed algorithms to maintain the CATH database.  

Following a career break, I was awarded a Daphne Jackson Research Fellowship hosted at  ICR and funded by the MRC, to develop the MoKCa database that analyses cancer associated mutations.

Role

Bioinformatics Academic Research Manager

My role as as Bioinformatics Academic Research Manager is to develop bioinformatic collaborations with the School of Life Sciences.  For instance, to support actvities in the Translational Drug Discovery Group at Sussex we have established computational biology and chemistry protocols to support the effective design of novel chemical modulators. Cheminformatic protocols have been designed for activities such as compound library selection, virtual screening, scaffold hopping and rational drug design.  We also have an established expertise in protein modelling and and small molecule docking.

 

For further information on our research, please see the Bioinformatics Lab Web Pages