Regulating the Transcriptome (C7132)

15 credits, Level 6

Autumn teaching

This module takes an up-to-the-minute look at the molecular mechanisms controlling RNA expression in prokaryotes and eukaryotes, focusing largely on gene transcription but also examining RNA processing events in eukaryotes.

We will examine the way in which bacteria control gene expression in response to different environmental cues through precisely coordinated transcription regulatory networks, and investigate the way in which eukaryotic transcriptional regulators control RNA polymerase recruitment and retention and modulate chromatin structure during transcriptional activation and repression.

Understanding these processes and mechanisms is fundamental for the study of health and disease, for example to aid the development of new antibiotics and decipher how gene regulatory networks are perturbed during cancer development.

Teaching

65%: Lecture
35%: Seminar

Assessment

30%: Coursework (Essay)
70%: Examination (Unseen examination)

Contact hours and workload

This module is 150 hours of work. This breaks down into 28 hours of contact time and 122 hours of independent study.

This module is running in the academic year 2018/19. We also plan to offer it in future academic years. It may become unavailable due to staff availability, student demand or updates to our curriculum. We’ll make sure to let our applicants know of such changes to modules at the earliest opportunity.

Courses

This module is offered on the following courses: