School of Life Sciences

photo of Darren Le Grand

Dr Darren Le Grand

Post:Project Leader (Biochemistry)
Location:CHICHESTER 2 Room 315C
Email:D.Le-Grand@sussex.ac.uk

Research expertise:
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Biography

Darren has over 20 years’ experience working in drug discovery at Novartis Pharmaceuticals in the UK. As a Medicinal chemist Darren worked on numerous projects, contributing to the discovery of several development candidates with three reaching phase I clinical studies. He has experience leading multi-disciplinary project teams, and played a leading role in the discovery of a potent potentiator of the Cystic Fibrosis Transmembrane Conductance Regulator that is currently in clinical trials.  Darren is a named inventor on over 20 published patents on diverse targets such as ion channel modulation, enzyme inhibition and GPCR antagonism.