Dr Irina Chuckowree
| Post: | Research Fellow in Medicinal Chemistry (Biochemistry) |
| Location: | ARUNDEL BUILDING 315 |
| Email: | I.Chuckowree@sussex.ac.uk |
Telephone numbers | |
| Internal: | 8419 |
| UK: | 01273 678419 |
| International: | +44 1273 678419 |
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Biography
Irina has extensive experience as a Medicinal Chemist in both the pharmaceutical industry and academia working on various drug targets: histone deacetylases (HDAC), class I phosphatidylinositol 3- and VEGFR-2 kinases, topoisomerases, multi-drug resistance associated protein (MRP1), plasminogen activator inhibitor-1 (PAI-1), cannabinoid receptor type 1 (CB1), and p53 tumour suppressor protein. Irina played a key role in identifying the Phase II topoisomerases inhibitor XR11576, and the Phase II PI3K inhibitors GDC-0941 and GDC-0980.