| Post: | Senior Lecturer in Bioinformatics |
| Location: | JMS Building 4B14 |
| Email: | S.Jones@sussex.ac.uk |
| Telephone numbers | |
| Internal: | 7553 |
| UK: | (01273) 877553 |
| International: | +44 1273 877553 |
Biography
Background
BSc Biology, University of York
PhD Biochemistry (Bioinformatics), University College London
Key repsonsibilities
Course Convenor : Programming for Bioinformatics, Genomics, Bioinformatics
Course Teaching: Biological Chemistry, Proteins Form and Function, Genomics, Programming for Bioinformatics, Research Methods.
Lead on E-GO Project: Evaluation and implementation of scalable e-learning tools for the creation of flexible and sustainable programmes
Research
Bioinformatics is a relatively 'new' field within biological sciences and sees the fusion of biology and computer science. The biological data we analyse using computer science techniques includes genome sequences, and transcriptome and proteome information. My research centres on the application of bioinformatics methods to the study of molecular interactions in protein sequences and structures. Specifically I am focussing on the characteristaion of protein-nucleic acid interactions; and I also have more general research interests in protein function annotation of genomic data.
Publications
Recent & Selected Publications
1. Spriggs RV, Murakami Y, Nakamura H & Jones S. (2009) Protein function annotation from sequence: prediction of residues interacting with RNA. Bioinformatics 25 p1492-1497.
2. Reynolds C, Damerell D & Jones S. (2009) ProtorP: A protein-protein interaction analysis server. Bioinformatics. 25 p413-414.
3. Ellis J.J & Jones S. (2008) Evaluating conformational changes in protein structures binding RNA. Proteins: Structure, Function and Bioinformatics 70 p1518-26.
4. Jones S and Murakami Y (2007) Patch prediction of protein interaction sites: validation of a scoring function for an online server. Lecture Notes in Bioinformatics. 4414 p303-113.
5. Ellis J.J, Broom M. & Jones S. (2007) Protein-RNA Interactions: structural analysis and functional classes Proteins: Structure, Function and Bioinformatics 66 p903-911.
6. Murakami Y & Jones S (2006) SHARP2: protein-protein predictions using patch analysis. Bioinformatics 22 p1794-1795.
7. Jones, S., vanHeyningen, P., Berman, H.M. & Thornton, J.M. (1999) Protein-DNA interactions: A structural analysis. Journal of Molecular Biology, 287, 877-896
8 . Jones, S. & Thornton, J.M. (1996) Principles of protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America, 93, 13-20